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Signs or symptoms of serotonin syndrome

Easily annoyed, Delirium, Change, Fits, Restlessness, Increased middle rate, Sweating, Shivering, Tremor, Cerebral status changes, Restlessness, Increased reflexes, Increased reflexes, Stiffness, Moving, Pain in the belly, Diarrhea, Perspiration, Increased heat, High blood pressure. All these are symptoms of serotonin syndrome. Just about all may appear usually within the first day following taking an overdose of serotonin drugs. This signs or symptoms are on mental processes stage, visceral anxious system level as well as SoNS level. Serotonin Toxidrome come usually following o.d. of serotonin drugs as well as drug combination that increase synaptic serotonin. Drugs that are know to stimulate high levels of serotonin are: MAOIs, TCAs, SSRIs, SNRIs, Bupropion, Tramadol, Fentany, Oxycodone, Hydrocodone, MDMA, MDA, Amphetamine, Sibutramine, Crack, Triptans, LSD, Panax Ginseg, Nutmed, Yohimbe, Syrian Rue, Ritonavir, Granisetron, Olanzapine, Valproate, Buspirone, Lithium, Linezolid, Dextromethorphan, Risperidone, Trypthophan, L-Dopa, Valproate, Amphetamine. Because serotonin toxidrome it's definitely not tested in the laboratory for diagnosis, symptoms tend to be the one need observed. The number one set of criteria to use to diagnose serotonin toxicity is Hunter Serotonin Toxicity Criteria.

Treatment for serotonin syndrome tend to be as follows: discontinuing drugs which produced the o.d. posible and also drugs which can contribute administration of serotonin antagonist (eg. cyproheptadine) for cut cases of toxicity for agitation, muscle tightness as well as capture like movements, benzodiazepines (Valium, Ativan) Intra venous liquids Considering that serotonin syndrome is certainly not simple to diagnose, prevention is wanted for any serotonin drugs mixture of that might cause 5-hydroxytryptamine toxicity.

''Dunkley, EJ, Isbister, GK, Sibbritt, D, Dawson, AH, Whyte, IM, The Hunter Serotonin Toxicity Criteria: simple and accurate diagnostic decision rules for serotonin toxicity, QJM 2003; 96:635-642 Prator BC. Serotonin syndrome symptoms. J Neurosci Nurs. 2006 Apr;38(2):102-5. Ford MD, Clinical Toxicology. 1st ed. Philadelphia, Pa: WB Saunders; 2001:150, 522, 547, 550.''